Cloud computing is hotter than ever before. The reason is quite simple: business organizations find it easier to integrate cloud solutions with their ongoing business operations. In addition, cloud solutions are often more cost-effective than deploying in-house servers and developing custom Information Technology (IT) enterprise tools. As more organizations continue to migrate their workloads and applications to the cloud, security issues will become more prominent, requiring a dynamic solution that offers secure communication pathways between complex IT environments. Cloud network segmentation and defense in depth (DiD) security model can provide a way forward.